Influence of therapeutic strategy on the quality of life of patients with endometriosis in three hospitals in Brazzaville

Abstract

Introduction: Endometriosis combines varying degrees of intensity with dysmenorrhea, deep dyspareunia and chronic pelvic pain, leading to undeniable repercussions and affecting the daily lives of women with a considerable alteration in the quality of life. The present study aimed to analyze the quality of life of patients treated for endometriosis in three hospitals in Brazzaville. Patients and method: Multicenter analytical cross-sectional study carried out from January 1 to June 30, 2022, comparing 52 patients treated as first-line hormonal therapy (estrogen-progestin contraceptives) for endometriosis and 45 others having benefited from primary conservative surgery. The patients were followed for at least two years. The validated French version of the Endometriosis Health Profile-5 (EHP-5) questionnaire was used to assess patients' quality of life. The variables studied were sociodemographic
and reproductive (age, level of education, gainful activity, marital status, parity), clinical (diagnosis time, evaluative time, digestive damage, ovarian and deep location), in relation to the quality of life and the evaluative period. Epi-Info 7.2.6.0 software was used for statistical analysis. The p-value of probability was considered significant for a value less than 0.05. Introduction: Endometriosis combines varying degrees of intensity with dysmenorrhea, deep dyspareunia and chronic pelvic pain, leading to undeniable repercussions and affecting the daily lives of women with a considerable alteration in the quality of life. The present study aimed to analyze the quality of life of patients treated for endometriosis in three hospitals in Brazzaville. Patients and method: Multicenter analytical cross-sectional study carried out from January 1 to June 30, 2022, comparing 52 patients treated as first-line hormonal therapy (estrogen-progestin contraceptives) for  endometriosis and 45 others having benefited from primary conservative surgery. The patients were followed for at least two years. The validated French version of the Endometriosis Health Profile-5 (EHP-
5) questionnaire was used to assess patients' quality of life. The variables studied were sociodemographic and reproductive (age, level of education, gainful activity, marital status, parity), clinical (diagnosis time, evaluative time, digestive damage, ovarian and deep location), in relation to the quality of life and the evaluative period. Epi-Info 7.2.6.0 software was used for statistical analysis. The p-value of probability was considered significant for a value less than 0.05.Introduction: Endometriosis combines varying degrees of intensity with  dysmenorrhea, deep dyspareunia and chronic pelvic pain, leading to undeniable repercussions and affecting the daily lives of women with a considerable alteration in the quality of life. The present study aimed to analyze the quality
of life of patients treated for endometriosis in three hospitals in Brazzaville. Patients and method: Multicenter analytical cross-sectional study carried out from January 1 to June 30, 2022, comparing 52 patients treated as first-line hormonal therapy (estrogen-progestin contraceptives) for endometriosis and 45 others having benefited from primary conservative surgery. The patients were
followed for at least two years. The validated French version of the Endometriosis Health Profile-5 (EHP-5) questionnaire was used to assess patients' quality of life. The variables studied were sociodemographic and reproductive (age, level of education, gainful activity, marital status, parity), clinical (diagnosis time, evaluative time, digestive damage, ovarian and deep location), in relation to the quality of life and the evaluative period. Epi-Info 7.2.6.0 software was used for statistical analysis. The p-value of probability
was considered significant for a value less than 0.05. Results: The patients treated medically as first-line treatment were younger (28 years vs. 32 years; p<0.05), with a low level of education (p<0.05), without income-generating activities (2.95 [1, 28-6.77]; p<0.05) and nulliparous (p<0.05). Quality of life was better in the event of first-line surgery (p<0.05) and influenced by age = 35 years (p<0.05); parity = 1 (p<0.005); the evaluation period = 36 months (p<0.05); deep location (p<0.05) and digestive involvement (p<0.05).
Conclusion. The choice of therapeutic strategy in cases of endometriosis must consider the epidemiological-clinical profile of the patient to improve her quality of life.